Motif ID: SOX{8,9,10}.p2

Z-value: 1.539


Transcription factors associated with SOX{8,9,10}.p2:

Gene SymbolEntrez IDGene Name
SOX10 6663 SRY (sex determining region Y)-box 10
SOX8 30812 SRY (sex determining region Y)-box 8
SOX9 6662 SRY (sex determining region Y)-box 9

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SOX9chr17_+_676287720.458.0e-02Click!
SOX10chr22_-_367104840.204.5e-01Click!


Activity profile for motif SOX{8,9,10}.p2.

activity profile for motif SOX{8,9,10}.p2


Sorted Z-values histogram for motif SOX{8,9,10}.p2

Sorted Z-values for motif SOX{8,9,10}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX{8,9,10}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_128883125 4.429 NM_002844
NM_001135648
 PTPRK

protein tyrosine phosphatase, receptor type, K

chr7_-_27171673 3.545 NM_152739
 HOXA9
homeobox A9
chr12_-_8706533 3.494 MFAP5
microfibrillar associated protein 5
chr7_-_27171648 3.252 HOXA9
homeobox A9
chr17_-_36996611 3.038 NM_000526
 KRT14
keratin 14
chr12_-_51173238 2.619 NM_005554
 KRT6A
keratin 6A
chr12_-_8706637 2.529 NM_003480
 MFAP5
microfibrillar associated protein 5
chr2_+_101680594 2.489 NM_004834
NM_145686
NM_145687
 MAP4K4


mitogen-activated protein kinase kinase kinase kinase 4


chr21_+_17807167 2.160 NM_001338
 CXADR
coxsackie virus and adenovirus receptor
chr11_-_27450808 1.964 NM_018490
 LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chr1_-_43196911 1.923 SLC2A1
solute carrier family 2 (facilitated glucose transporter), member 1
chr5_-_16989371 1.911 NM_012334
 MYO10
myosin X
chr1_-_94475504 1.878 ARHGAP29
Rho GTPase activating protein 29
chr12_+_52665196 1.727 NM_017409
 HOXC10
homeobox C10
chr7_+_134114957 1.711 CALD1
caldesmon 1
chr1_-_95165037 1.704 CNN3
calponin 3, acidic
chr7_+_121300394 1.633 NM_002851
 PTPRZ1
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr10_+_71482362 1.594 NM_018649
 H2AFY2
H2A histone family, member Y2
chr10_+_71482542 1.571 H2AFY2
H2A histone family, member Y2
chr4_-_186969041 1.570 NM_001145672
 SORBS2
sorbin and SH3 domain containing 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
6.66 1.13e-02 GO:0003009 skeletal muscle contraction
2.52 1.37e-02 GO:0007156 homophilic cell adhesion
2.17 4.13e-04 GO:0030029 actin filament-based process
2.08 1.54e-02 GO:0030036 actin cytoskeleton organization
1.41 1.50e-02 GO:0007399 nervous system development
1.32 1.75e-05 GO:0007275 multicellular organismal development
1.32 1.10e-04 GO:0048856 anatomical structure development
1.32 4.62e-04 GO:0048731 system development
1.30 2.41e-05 GO:0032502 developmental process
1.26 6.47e-06 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
2.39 2.53e-02 GO:0030016 myofibril
2.36 4.60e-02 GO:0044449 contractile fiber part
2.14 2.82e-02 GO:0070161 anchoring junction
1.84 2.20e-02 GO:0015629 actin cytoskeleton
1.72 1.41e-03 GO:0030054 cell junction
1.20 2.50e-02 GO:0005886 plasma membrane
1.20 2.75e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
2.03 4.68e-04 GO:0003779 actin binding
1.78 4.75e-04 GO:0008092 cytoskeletal protein binding